The cascade of multiorgan dysfunction in COVID 19 patients. A case presentation.

By, Dr. Sc. Migena QATO, Prof. Dr. Najada COMO, Dr. Sc. Esmeralda META, Msc. Afrim YZEIRI, Prof. Asoc. Dr. Albana GJYZELI

Abstract
Introduction: The SARS COV 2 epidemic has caused thousands of deaths due to different mechanisms of organ injury, starting from the respiratory and cardiovascular system and followed with significant involvement of kidneys, liver, pancreas and several metabolic dysfunctions which all caused a rapid progression of disease leading to death within the second week of hospitalization. Method: We present the case of a 67-year-old woman who died within 24 hours of admission due to a rapid deterioration of her clinical condition with several successive complications. Results: The patient developed a fulminant clinical course, starting with flu-like prodromal symptoms proceeding to altered mental status, metabolic acidosis, acute respiratory distress syndrome (ARDS) and renal failure within 3 days. The rapid involvement of several vital organs predicted a poor diagnosis since the first evaluation in admission which resulted to be irreversible. Conclusion: The predictors of poor prognosis and severity may help clinicians to apply therapeutic regimens in order to avoid disease progression to multiorgan damage and potentially death.
Key words: Covid-19, multi-organ dysfunction, cascade, case report.